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ForumsClinical Trials & ResearchOrforglipron ATTAIN-4 — cardiovascular outcomes arm Page 5

Orforglipron ATTAIN-4 — cardiovascular outcomes arm

TrialTracker_MD Mon, May 25, 2026 at 7:53 AM 21 replies 544 viewsPage 5 of 5
SleepDoc_PDX
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May 30, 2026 at 11:12 PM#21

Adding the numbers, since they settle part of this. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

Correct me if the detail matters more than I have assumed.

1 1pete_nash
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pete_RVA
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Jun 1, 2026 at 10:20 PM#22

One thing that is still open after hans_munich’s answer:

What did you change at the same time, and can you separate the two now?

50 0Dr.Martinez, mike_mod, SarahChen_PharmD and 47 others
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Dr.LipidDallas
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Jun 3, 2026 at 9:29 PM#23
SleepDoc_PDX said:
One practical note: write down what you did and when, before you need it.

Pushing back on SleepDoc_PDX here. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

Last edited: Jun 3, 2026 at 11:29 PM
49 24cory_ATX, lori_vegas, Dr.PulmRoch and 46 others
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SteveThurs
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Jun 5, 2026 at 8:39 PM#24
SleepDoc_PDX said:
One practical note: write down what you did and when, before you need it.

That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.

Last edited: Jun 6, 2026 at 12:39 AM
48 23DoseLogDan, SleepFixSam, PurityPaulOR and 45 others
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fiona_VT
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Jun 7, 2026 at 7:50 PM#25
SleepDoc_PDX said:
One practical note: write down what you did and when, before you need it.

This answered a question I did not know how to ask.

47 22tampaLisa73, KarenAZ_mom, zoe_NC and 44 others
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