sarah_TO said:

Propensity score matching studies and the trial evidence: when RCTs aren't available for a specific question, propensity score-matched observational…

Second this. Nothing to add that would improve it.

labquiet_amy said:

Practical: whatever you change, write down the date and the reason.

Thank you for spelling out the reasoning rather than just the conclusion.

Adding the clinical framing, because it changes how the question reads. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

VendorMark said:

Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

Same experience, arrived at from the opposite direction. The detail I would add is minor and it is already implied above.

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here.