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ForumsCompounding & FormulationBacteriostatic water sourcing and sterility considerations — July 2024 Page 6

Bacteriostatic water sourcing and sterility considerations — July 2024

Dr.GastroMayo Tue, Dec 17, 2024 at 10:11 AM 48 replies 2,414 viewsPage 6 of 10
roxy_nash
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Feb 26, 2025 at 3:41 PM#26
PharmacoVig_BOS said:
Sharing my dosing arithmetic titration experience with compounded semaglutide — I have been tracking injection volumes meticulously: Using 5mg/2mL…

That reframing is the part I needed.

Last edited: Feb 26, 2025 at 9:41 PM
39 14josh_phd_bmore, roxy_nash, tony_orlando and 36 others
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NurseAsh_DET
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Detroit, MI
Mar 7, 2025 at 7:25 PM#27

From the other side of the consultation, briefly.

Regarding dosing arithmetic multi-dose vial contamination prevention: after reconstituting, I wipe the vial stopper with a fresh alcohol swab before EVERY single draw. I also never touch the stopper with my fingers and use a new needle for each draw.

Even with bacteriostatic water preservative, contamination is cumulative. One sloppy draw can introduce bacteria that multiply over days. Aseptic technique isn't optional — it's essential for injectable medications.

38 13ricardo_MIA, BrianDallas92, labquiet_amy and 35 others
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MeganSA_TX
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San Antonio, TX
Mar 16, 2025 at 11:15 PM#28
NurseAsh_DET said:
Regarding dosing arithmetic multi-dose vial contamination prevention: after reconstituting, I wipe the vial stopper with a fresh alcohol swab before…

Same experience, arrived at from the opposite direction.

37 12JessicaM_2024, TomFromTexas, mike.trainer_LA and 34 others
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Dr.NateNeph
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Mar 26, 2025 at 3:10 AM#29
NurseAsh_DET said:
Regarding dosing arithmetic multi-dose vial contamination prevention: after reconstituting, I wipe the vial stopper with a fresh alcohol swab before…

Coming at NurseAsh_DET’s question from a different direction. The pattern that distinguishes a bad batch from an exit is behaviour rather than product. A bad batch comes with communication, a reshipment offer and a batch number. An exit comes with slower replies, pressure toward less reversible payment methods, sudden discounting, and the same reassurance repeated without any new information. The product tells you less than the correspondence does.

Happy to go further on any of that.

Last edited: Mar 26, 2025 at 5:10 AM
36 11B12Beth, RickReta_CO, PharmHunterJen and 33 others
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Dr.GastroMayo
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Apr 4, 2025 at 7:10 AM#30

Closing the loop on my own question.

Went back through my own correspondence with an earlier supplier and the warning signs were all there in the replies, weeks before the quality changed. I was reading the product and not the behaviour.

14 14InsuranceTom, WendyG_ATL, SaraMom3 and 11 others
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