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ForumsClinical Trials & ResearchTRIUMPH program (retatrutide) — November 2025 Page 2

TRIUMPH program (retatrutide) — November 2025

adam_van Thu, Apr 9, 2026 at 9:32 AM 10 replies 776 viewsPage 2 of 2
COA_Karl
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Apr 10, 2026 at 9:38 AM#6
TirzTom said:
Start from the measurement rather than the conclusion.

I would rather people stopped quoting the 24% as if it were a licensed outcome. It is a phase 2 result in a few hundred participants with no cardiovascular endpoint and no long-term safety data, and this board has a habit of treating pipeline numbers as settled.

6 9matt_MKE, Dr.ReproEndo, lucas_SP_BR and 3 others
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kate.chem
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Apr 10, 2026 at 7:14 PM#7

Adding the numbers, since they settle part of this. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

Last edited: Apr 10, 2026 at 10:14 PM
7 10VanRx_Mike, steve_okc, dave_SLC and 4 others
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Dr.ObesityMed
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Apr 11, 2026 at 4:50 AM#8
COA_Karl said:
I would rather people stopped quoting the 24% as if it were a licensed outcome.

Adding the part of the answer the thread has not reached. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

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amy_econ_NJ
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Apr 11, 2026 at 2:25 PM#9

Following on from LabKate — and this may be the naive question:

What the phase 2 dropout pattern implies about how the phase 3 tolerability will read?

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adam_van
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Apr 13, 2026 at 12:26 PM#10

OP back with an update, since a thread like this is useless without one.

Rereading it with the dropout table open changed my view. I still think it is the most interesting molecule in the pipeline; I no longer think the 24% is the number that will end up on a label.

Last edited: Apr 13, 2026 at 4:26 PM
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