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ForumsTirzepatide (Mounjaro / Zepbound)5mg → 10mg → 15mg titration — March 2026 Page 7

5mg → 10mg → 15mg titration — March 2026

BiostatsBrad Wed, Jun 4, 2025 at 8:46 PM 49 replies 2,557 viewsPage 7 of 10
NauseaFreeNow
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Jun 23, 2025 at 3:08 AM#31
TrialNerd_Beth said:
Worth answering the question that was asked rather than the one behind it.

There is a second half to this that has not been said yet. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

41 16stefan_berlin, Dr.EM_Chicago, pete_RVA and 38 others
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BethLabQueen
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Jun 24, 2025 at 11:32 AM#32

One concrete data point for the thread. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

40 15Dr.PulmRoch, maya_sedona, stefan_berlin and 37 others
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traveltech_sara
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Jun 25, 2025 at 7:56 PM#33

One thing that is still open after TrialNerd_Beth’s answer:

How would you tell the difference between that and the alternative explanation?

39 14wanda_boise, NurseAsh_DET, BenResearch_OR and 36 others
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pam_columbus
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Jun 27, 2025 at 4:21 AM#34
BethLabQueen said:
If you are going to change something, change one thing and give it long enough to express itself.

Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.

38 13tammy_FL, Dr.LipidDallas, alex_tucson and 35 others
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Dr.EndoIndy
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Jun 28, 2025 at 12:47 PM#35
BethLabQueen said:
If you are going to change something, change one thing and give it long enough to express itself.

That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.

37 12SandraNC_45, Dr.EndoIndy, tom_AK and 34 others
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