BariatricNurseD said:

Propensity score matching studies and the trial evidence: when RCTs aren't available for a specific question, propensity score-matched observational…

Fair, and it stops being fair at the extremes. The middle of the range is well understood; the ends are where the honest answer is that nobody knows.

rachel_ABQ said:

Dr.GutHealth said: ...regarding the trial evidence...

Thank you for spelling out the reasoning rather than just the conclusion. Sending this to two other people who asked me the same thing last week.

BariatricNurseD said:

Propensity score matching studies and the trial evidence: when RCTs aren't available for a specific question, propensity score-matched observational…

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

One concrete data point for the thread. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful.