Dr.BariatricHTX said:Dr.RaviCardio said: ...regarding the trial evidence...
Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.
hyun_seoul said:Bayesian meta-analysis perspective on the trial evidence: traditional frequentist meta-analyses report point estimates and confidence intervals.
This answered a question I did not know how to ask.
Dr.BariatricHTX said:Dr.RaviCardio said: ...regarding the trial evidence...
Pushing back on Dr.BariatricHTX here. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.
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View ResultsOne concrete data point for the thread. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.