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Evidence-based GLP-1 & peptide discussion since 2023
ForumsClinical Trials & ResearchEfinopegdutide — 6 month update Page 3

Efinopegdutide — 6 month update

RetaRick_CA Tue, Jan 27, 2026 at 9:48 AM 13 replies 1,039 viewsPage 3 of 3
LarryQC_SD
Senior Member
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Feb 1, 2026 at 12:28 PM#11
DebRD_ATL said:
Bayesian meta-analysis perspective on the trial evidence: traditional frequentist meta-analyses report point estimates and confidence intervals.

That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.

Last edited: Feb 1, 2026 at 1:28 PM
4 2NurseKim_ATL, paul_denver, TinaHashiRN and 1 other
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DadBodDave
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Ohio
Feb 3, 2026 at 6:17 AM#12
Admin said:
Propensity score matching studies and the trial evidence: when RCTs aren't available for a specific question, propensity score-matched observational…

Saving this. It is the first explanation that did not require me to already understand it. Printing the relevant bit and taking it with me.

Last edited: Feb 3, 2026 at 9:17 AM
5 3JenMemphis, pat_auckland, Dr.GastroMayo and 2 others
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zoe_NC
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Charlotte, NC
Feb 5, 2026 at 12:05 AM#13
DebRD_ATL said:
Bayesian meta-analysis perspective on the trial evidence: traditional frequentist meta-analyses report point estimates and confidence intervals.

This is where I part company with the consensus forming above. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.

Last edited: Feb 5, 2026 at 1:05 AM
6 4james_edin, FranDenver, Dr.BariatricHTX and 3 others
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dave_SLC
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Salt Lake City, UT
Feb 6, 2026 at 5:52 PM#14

The figures, for anyone assembling their own picture. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

7 5FranDenver, Dr.BariatricHTX, LindaRN_retired and 4 others
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mike_mod
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Feb 8, 2026 at 11:39 AM#15

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source.

8 6PurityPaulOR, MaxMetOK, MounjBrad and 5 others
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