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ForumsTirzepatide (Mounjaro / Zepbound)Tirzepatide and kidney function — need advice Page 4

Tirzepatide and kidney function — need advice

MikeNYC_runner Sun, Oct 6, 2024 at 6:53 PM 18 replies 2,010 viewsPage 4 of 4
DerekSJ_a1c
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Oct 12, 2024 at 9:30 AM#16
Dr.EM_Chicago said:
Dose-response modeling for tirzepatide: Emax model fitting to the STEP/SURMOUNT dose-finding data shows: Semaglutide: ED50 ≈ 0.6mg, Emax ≈ -18%, Hill…

This matches mine closely enough to be worth saying so out loud. Nothing to add that would improve it.

Last edited: Oct 12, 2024 at 2:30 PM
17 15adam_van, Dr.SurgeonPGH, rachel_ABQ and 14 others
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mark_tokyo
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Oct 12, 2024 at 2:03 PM#17
PeptideChemSF said:
One practical note: write down what you did and when, before you need it.

Same experience, arrived at from the opposite direction. I had assumed I was the exception until I read this.

Last edited: Oct 12, 2024 at 5:03 PM
18 16bri_stats, pete_manc_UK, anna.melb_AU and 15 others
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Dr.AddMedPHL
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Oct 12, 2024 at 6:36 PM#18
PeptideChemSF said:
One practical note: write down what you did and when, before you need it.

Adding the part of the answer the thread has not reached. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

19 17mike.trainer_LA, sarah_nash92, FitDadDave and 16 others
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bri_stats
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Oct 12, 2024 at 11:09 PM#19

Adding the numbers, since they settle part of this. Worth stating the units and the reference range whenever you post a number here. A large fraction of the apparent disagreement in these threads is two people using different units and both being right.

Worth separating that from renal function, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

20 18JessicaM_2024, TomFromTexas, mike.trainer_LA and 17 others
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Admin
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Oct 13, 2024 at 3:42 AM#20

Moderator note: the sourcing question belongs in the vendor section and has been split out. Carry on.

42 15PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 39 others
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