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Evidence-based GLP-1 & peptide discussion since 2023
ForumsTirzepatide (Mounjaro / Zepbound)My appetite is literally gone is this normal at 10mg — November 2025 Page 7

My appetite is literally gone is this normal at 10mg — November 2025

PeptideSynthNJ Thu, May 30, 2024 at 7:10 AM 45 replies 2,266 viewsPage 7 of 9
Dr.LipidDallas
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Jun 8, 2024 at 9:56 PM#31
dan_philly said:
Worth stating the units and the reference range whenever you post a number here.

Thank you for spelling out the reasoning rather than just the conclusion. I will report back once I have actually tried it.

28 1pam_stl, wei_SG, cory_ATX and 25 others
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paige_pharma
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Jun 9, 2024 at 12:40 PM#32

Clinical perspective, offered as context rather than as advice. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Last edited: Jun 9, 2024 at 1:40 PM
29 2Dr.SurgeonPGH, rachel_ABQ, traveltech_sara and 26 others
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mike_nyc
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Jun 10, 2024 at 3:24 AM#33
paige_pharma said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Can confirm. Same sequence, different timescale. The detail I would add is minor and it is already implied above.

30 3Dr.EM_Chicago, pete_RVA, CarlaRPh_TPA and 27 others
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cory_ATX
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Jun 10, 2024 at 6:07 PM#34
paige_pharma said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Coming at paige_pharma’s question from a different direction. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

31 4Dr.PathRoch, mona_PHX, andrew_nyc and 28 others
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Dr.RaviCardio
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Jun 11, 2024 at 8:50 AM#35

The figures, for anyone assembling their own picture. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

Last edited: Jun 11, 2024 at 9:50 AM
32 5jason_sac26, chris_chi24, tampaLisa73 and 29 others
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