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Evidence-based GLP-1 & peptide discussion since 2023
ForumsVerified VendorsUS-based vendors charge 4-5x more — are you paying for quality or convenience? Page 3

US-based vendors charge 4-5x more — are you paying for quality or convenience?

InsuranceTom Mon, Mar 23, 2026 at 7:29 PM 37 replies 1,138 viewsPage 3 of 8
Dr.ObesityLA
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Mar 24, 2026 at 6:09 PM#11
Dr.LipidDallas said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Correct, and worth adding that it is reversible. Nothing being described here is a one-way door, which changes how cautious it is reasonable to be.

38 11zoe_NC, Dr.ObesityLA, NurseKim_ATL and 35 others
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laura_annarbor
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Mar 25, 2026 at 1:12 PM#12
Dr.GastroMayo said:
Right, and one flattering data point from a group buy is not consistency.

Saving this. It is the first explanation that did not require me to already understand it. Taking it to my next appointment.

39 12emily_PDX, Dr.SleepRoch, laura_annarbor and 36 others
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tony_orlando
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Mar 26, 2026 at 8:14 AM#13
Dr.LipidDallas said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.

40 13ZaraB_AL, JakeSmashed95, NauseaFreeNow and 37 others
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BiostatsBrad
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Mar 27, 2026 at 3:16 AM#14

Adding the numbers, since they settle part of this. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

Correct me if the detail matters more than I have assumed.

41 14james_edin, FranDenver, Dr.BariatricHTX and 38 others
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mike_mod
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Mar 27, 2026 at 10:18 PM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Carry on.

Last edited: Mar 28, 2026 at 12:18 AM
42 15PurityPaulOR, MaxMetOK, MounjBrad and 39 others
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