PurityPaulOR said:The distinction that resolves most of these threads is between what is true on average and what is true for one person.
I read this differently from PurityPaulOR, on substance rather than tone. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.
Adding the numbers, since they settle part of this. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.
kate.chem said:This treats a plausible mechanism as a demonstrated one.
Coming at kate.chem’s question from a different direction. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.
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Browse GL BiochemA narrower follow-up, since the general answer is now clear:
Was that from a primary source or from a summary of one?
Closing the loop on my own question.
Closing this out. What actually changed my mind was the point about waiting for a trend instead of reading a single measurement, which is embarrassing in hindsight and worth saying anyway.