Dr.CardioMD said:Cold chain shipping for storage and cold: my last order arrived with the cold pack completely melted and the vial at room temperature.
Mine went the same way, slower. I had assumed I was the exception until I read this.
Dr.GutHealth said:Storage best practices for compounded storage and cold: Unreconstituted lyophilized powder: refrigerate (36-46°F), good for 12+ months Reconstituted…
Storage question about storage and cold: my pen was left out of the fridge for 8 hours. Is it still good?
Per the manufacturer, both Ozempic and Wegovy pens can be stored at room temp (up to 86°F) for up to 28 days after first use. So yes, it should be fine as long as it wasn't exposed to extreme heat.
The figures, for anyone assembling their own picture. Worth knowing that the injection site changes very little. Abdomen, thigh and upper arm are bioequivalent for semaglutide, so a site change is not a plausible explanation for a bad week.
Worth separating that from semaglutide, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.
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Browse GL BiochemFollowing on from Dr.GutHealth — and this may be the naive question:
How much of the between-person variation is pharmacokinetic and how much is just adherence measured badly?
Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Carry on.