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ForumsSemaglutide (Ozempic / Wegovy)Semaglutide and alcohol intolerance — mechanism and prevalence data Page 4

Semaglutide and alcohol intolerance — mechanism and prevalence data

NeuroNate Thu, Apr 30, 2026 at 9:05 AM 23 replies 623 viewsPage 4 of 5
wei_SG
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May 2, 2026 at 6:12 PM#16
VanRx_Mike said:
NeuroNate said: ...but the FDA says semaglutide...

Agreed, and if the change has opened a harder question about someone's drinking, that belongs with a service rather than a thread.

Worth separating that from alcohol, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

Last edited: May 2, 2026 at 7:12 PM
19 17WendyG_ATL, SaraMom3, Dr.MetabolicMD and 16 others
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wanda_boise
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May 3, 2026 at 12:42 AM#17
wei_SG said:
Agreed, and if the change has opened a harder question about someone's drinking, that belongs with a service rather than a thread.

Same pattern here, and in the same order. Posting only so the count is not one.

20 18marco_milano, pam_columbus, nick_SD_fit and 17 others
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BenResearch_OR
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May 3, 2026 at 7:12 AM#18
wei_SG said:
Agreed, and if the change has opened a harder question about someone's drinking, that belongs with a service rather than a thread.

There is a second half to this that has not been said yet. Reduced interest in alcohol is one of the most consistently reported off-target effects, and the mechanism is plausibly the same reward-salience pathway that quiets food noise. The practical part people get wrong is that tolerance changes: less food in the stomach, faster gastric emptying of liquid relative to solids, and a smaller body mean the same two drinks land considerably harder than they used to.

21 19Dr.NateNeph, PharmD_Rodriguez, julia.endo and 18 others
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wendy_avl
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May 3, 2026 at 1:41 PM#19

Adding the numbers, since they settle part of this. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

22 20PharmHunterJen, TomTeleRx, DoseLogDan and 19 others
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mike_mod
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May 3, 2026 at 8:10 PM#20

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. No action needed from anybody.

44 17PurityPaulOR, MaxMetOK, MounjBrad and 41 others
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