🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsMASH / Liver DiseaseDe novo lipogenesis reduction on GLP-1 — mechanistic hepatology Page 4

De novo lipogenesis reduction on GLP-1 — mechanistic hepatology

MASHdoc_SA Mon, Jun 1, 2026 at 1:48 AM 17 replies 523 viewsPage 4 of 4
BiostatsBrad
Member
456
2,345
Jul 2024
Durham, NC
Jun 3, 2026 at 1:33 AM#16
pete_nash said:
Start from the measurement rather than the conclusion.

Adding a me-too, because a thread of one person's experience is not much use.

8 6LindaRN_retired, tommy_boulder, hyun_seoul and 5 others
Reply Quote Save Share Report
paige_pharma
Member
289
1,234
Sep 2024
Omaha, NE
Jun 3, 2026 at 5:37 AM#17

A narrower follow-up, since the general answer is now clear:

How long did you give it before you decided it was working?

9 7Dr.SurgeonPGH, rachel_ABQ, traveltech_sara and 6 others
Reply Quote Save Share Report
Dr.EndoEP
Member
267
1,234
Oct 2024
El Paso, TX
Jun 3, 2026 at 9:41 AM#18
NicoleRaleigh said:
For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

This is where I part company with the consensus forming above. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

Ask again with the specifics and you will get a better answer than this one.

10 8FranDenver, Dr.BariatricHTX, LindaRN_retired and 7 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides

GL Biochem (Shanghai) Ltd. — Direct Manufacturer

Est. 1998. The synthesis house behind the vials you send for testing. ISO 9001 and cGMP certified, 1,500+ staff, batch-specific COA with every order.

Browse GL Biochem
hank_denver
Member
278
1,234
Sep 2024
Denver, CO
Jun 3, 2026 at 1:45 PM#19
NicoleRaleigh said:
For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

True, with the qualification that this is a self-selected group. The people for whom it did not work post less, and that shapes everything we think we know.

Last edited: Jun 3, 2026 at 5:45 PM
11 9fiona_VT, denise_HTX, raj_cambridge and 8 others
Reply Quote Save Share Report
Admin
Administrator
2,456
9,812
Oct 2023
Online
Jun 3, 2026 at 5:49 PM#20

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here.

33 6PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 30 others
Reply Quote Save Share Report

Similar Threads

Survodutide MASH Phase 2b — histological improvement data9 replies
Semaglutide and MASH — liver fat reduction quantification13 replies
Non-invasive MASH biomarkers — FibroScan, ELF, FIB-4 on GLP-110 replies
ALT normalization rates on GLP-1 — pooled trial data20 replies
GLP-1 hepatoprotection — direct vs indirect mechanisms16 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register