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ForumsExercise & Body CompositionRecovery optimization on GLP-1 — sleep, HRV, and protein timing

Recovery optimization on GLP-1 — sleep, HRV, and protein timing

hank_denver Thu, May 14, 2026 at 5:10 AM 9 replies 513 viewsPage 1 of 2
hank_denver
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Denver, CO
May 14, 2026 at 5:10 AM#1

My appetite is suppressed enough that hitting a protein target is now the hardest part of the day, and everything I read assumes I can simply eat more.

The arithmetic that makes it tractable: reference weight in kg times 1.6 gives the target; divide by four for a per-sitting figure; then find four foods that hit that figure in a volume you can actually finish. Most people need two of the four to be liquid or semi-liquid early on.

The bit I cannot resolve on my own is whether the RDA is the wrong reference entirely during rapid weight loss, and what the actual target should be.

Numbers rather than impressions, if you have them.

24 19ingrid_STO, pete_nash, hank_denver and 21 others
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Dr.SportsMedIN
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Indianapolis, IN
May 14, 2026 at 6:50 AM#2

Short answer first, then the reasoning. The RDA is the wrong reference and it is worth understanding why. 0.8 g/kg is the intake at which nitrogen balance is not negative in healthy weight-stable adults — a floor for deficiency prevention, not an optimum, and derived in a population that is not in a deficit. In a substantial energy deficit, protein requirement rises because amino acids are being oxidised for energy and because muscle protein synthesis is blunted. The literature on preserving lean mass during weight loss lands around 1.4 to 2.0 g/kg of reference body weight, which is roughly two to two and a half times the RDA.

Ask again with the specifics and you will get a better answer than this one.

23 18lisa_labSD, adam_van, Dr.SurgeonPGH and 20 others
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BiostatsBrad
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Durham, NC
May 14, 2026 at 8:30 AM#3
Dr.SportsMedIN said:
The RDA is the wrong reference and it is worth understanding why.

Agreed on the target, with the caveat that reference weight and current weight are different numbers. Using current weight at the start of a large loss produces a target that is both unachievable and unnecessary.

22 17FranDenver, Dr.BariatricHTX, LindaRN_retired and 19 others
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fiona_glasgow
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May 14, 2026 at 10:10 AM#4
hank_denver said:
My appetite is suppressed enough that hitting a protein target is now the hardest part of the day, and everything I read assumes I can simply eat…

This matches mine closely enough to be worth saying so. Distribution matters less than total but it is not nothing. Roughly 25 to 40g per sitting with enough leucine to trigger synthesis, three or four times a day, is more effective than the same total in one enormous evening meal — and on a suppressed appetite the enormous evening meal is the one you will not finish anyway.

21 16JessicaH_TX, KevinCompounds, TirzTom and 18 others
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NurseLeah_Nash
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Nashville, TN
May 14, 2026 at 7:58 PM#5

From the other side of the consultation, briefly.

DEXA scan update relevant to protein intake:

Scanned at months 0, 6, and 12. Here are the body comp numbers:

BaselineMonth 6Month 12
Total mass271 lbs211 lbs208 lbs
Fat mass111 lbs71 lbs43 lbs
Lean mass149 lbs154 lbs155 lbs
Body fat %40%34%22%

Lean mass preserved — actually GAINED 1-2 lbs thanks to progressive overload + 1.5g/kg protein. The protein intake discussion needs to include body comp data, not just scale weight.

20 15Dr.NateNeph, PharmD_Rodriguez, julia.endo and 17 others
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