SarahChen_PharmD said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
Mine went the same way, slower. I had assumed I was the exception until I read this.
SarahChen_PharmD said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
There is a second half to this that has not been said yet. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.
Happy to go further on any of that.
Adding the numbers, since they settle part of this. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.
Ask again with the specifics and you will get a better answer than this one.
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Shop Reference StandardsFollowing on from SarahChen_PharmD — and this may be the naive question:
How much of the between-person variation is pharmacokinetic and how much is just adherence measured badly?
Closing the loop on my own question.
Six weeks on from posting: I stopped reading the weekly number and started reading a four-week average, and the "stall" I opened this thread about was a 1.8kg loss I could not see.