Dr.ReproEndo said:It is worth asking what the claim would look like if it were false.
Fair, and it stops being fair at the extremes. The middle of the range is well understood; the ends are where the honest answer is that nobody knows.
MikeFit_NJ said:Liver enzyme update related to liver and MASH: I had mildly elevated ALT/AST at baseline (likely NAFLD).
Thank you for spelling out the reasoning rather than just the conclusion.
Dr.ReproEndo said:It is worth asking what the claim would look like if it were false.
I read this differently from Dr.ReproEndo, on substance rather than tone. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.
I would rather be corrected than agreed with, if it comes to it.
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Shop Reference StandardsThe figures, for anyone assembling their own picture. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.