paige_pharma said:The distinction that resolves most of these threads is between what is true on average and what is true for one person.
Agreed on the mechanism, with the caveat that the head-to-head used semaglutide 1mg, not 2.4mg. It is still the best direct evidence available, but it is not the comparison most people think they are citing.
Dr.NateNeph said:Practical: whatever you change, write down the date and the reason.
That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.
Dr.NateNeph said:Practical: whatever you change, write down the date and the reason.
Saving this. It is the first explanation that did not require me to already understand it. Printing the relevant bit and taking it with me.
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View ResultsClinical perspective, offered as context rather than as advice. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.
Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. No action needed from anybody.