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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOther Peptides & Research CompoundsCerebrolysin — my results so far Page 3

Cerebrolysin — my results so far

BrianDallas92 Sat, Jun 14, 2025 at 3:16 AM 15 replies 1,536 viewsPage 3 of 3
PurityPaulOR
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Jun 14, 2025 at 10:34 PM#11
PharmD_Rodriguez said:
Semaglutide structural biology relevant to the pharmacology: semaglutide is a 31-amino acid peptide with 94% homology to native GLP-1(7-36).

No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.

35 8Dr.LeslieOBGYN, MikeNYC_runner and 32 others
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MikeKY_noInsulin
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Jun 15, 2025 at 12:18 PM#12
AttorneyGrant said:
The pharmacokinetics explain nearly every practical question asked here.

Saving this. It is the first explanation that did not require me to already understand it. Adding it to my notes with a link back to this thread.

36 9hannah_MT, Dr.SportsMedIN, amy_econ_NJ and 33 others
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hannah_MT
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Jun 16, 2025 at 2:02 AM#13
PharmD_Rodriguez said:
Semaglutide structural biology relevant to the pharmacology: semaglutide is a 31-amino acid peptide with 94% homology to native GLP-1(7-36).

This is where I part company with the consensus forming above. I think the framing smuggles in the conclusion. Ask it the other way round and the obvious answer reverses, which usually means the question is doing the work.

37 10MaxMetOK, MounjBrad, nick_newbie and 34 others
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raj_cambridge
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Jun 16, 2025 at 3:46 PM#14

The figures, for anyone assembling their own picture. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

Last edited: Jun 16, 2025 at 4:46 PM
38 11PharmHunterJen, TomTeleRx, DoseLogDan and 35 others
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Admin
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Jun 17, 2025 at 5:29 AM#15

Moderator note: the sourcing question belongs in the vendor section and has been split out.

39 12PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 36 others
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