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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab Results12-month metabolic panel comparison — before and after GLP-1 Page 5

12-month metabolic panel comparison — before and after GLP-1

DataDave Mon, Jun 8, 2026 at 4:31 PM 22 replies 610 viewsPage 5 of 5
MASHdoc_SA
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San Antonio, TX
Jun 8, 2026 at 7:16 PM#21

Clinical perspective, offered as context rather than as advice. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

2 0TirzTom, TrialTracker_MD
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TrialNerd_Beth
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Jan 2024
Bethesda, MD
Jun 8, 2026 at 8:18 PM#22
MASHdoc_SA said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Second this. The detail I would add is minor and it is already implied above.

3 1PharmHunterJen, TomTeleRx, DoseLogDan
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zoe_NC
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Nov 2024
Charlotte, NC
Jun 8, 2026 at 9:20 PM#23
MASHdoc_SA said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

There is a second half to this that has not been said yet. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

Last edited: Jun 8, 2026 at 10:20 PM
4 2james_edin, FranDenver, Dr.BariatricHTX and 1 other
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stefan_berlin
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Berlin, DE
Jun 8, 2026 at 10:22 PM#24

One concrete data point for the thread. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

I would rather be corrected than agreed with, if it comes to it.

5 3TirzTom, TrialTracker_MD, JennaRN and 2 others
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rachel_ABQ
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Dec 2024
Albuquerque, NM
Jun 8, 2026 at 11:24 PM#25

A narrower follow-up, since the general answer is now clear:

What did you change at the same time, and can you separate the two now?

6 4Dr.CardioMD, EndoResFellow, PharmacoVig_BOS and 3 others
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