Dr.PeteFamMed said:

Electrolyte monitoring on hydration — especially important during early titration when GI effects are most pronounced: Sodium: 140 mEq/L (normal, but…

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

Ask again with the specifics and you will get a better answer than this one.

Adding the numbers, since they settle part of this. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

sarah.morrison said:

The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is…

Adding the part of the answer the thread has not reached. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

Following on from emma_london — and this may be the naive question:

What would you measure differently if you were starting again?

OP back with an update, since a thread like this is useless without one.

Following up because I said I would. I changed one thing, left everything else alone, and waited the full interval before looking. It resolved, and I cannot prove which half of that did it.