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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOther Peptides & Research CompoundsTB-500 for the shoulder pain that started after weight loss — 12 month update Page 3

TB-500 for the shoulder pain that started after weight loss — 12 month update

DebRD_ATL Sat, Apr 26, 2025 at 6:08 AM 38 replies 2,224 viewsPage 3 of 8
InsuranceTom
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Apr 27, 2025 at 6:32 AM#11
PharmacoVig_BOS said:
Semaglutide structural biology relevant to the pharmacology: semaglutide is a 31-amino acid peptide with 94% homology to native GLP-1(7-36).

True, with the qualification that this is a self-selected group. The people for whom it did not work post less, and that shapes everything we think we know.

45 18lisa_labSD, adam_van, Dr.SurgeonPGH and 42 others
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anna.melb_AU
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Apr 27, 2025 at 10:44 AM#12
JennaRN said:
The pharmacokinetics explain nearly every practical question asked here.

Bookmarking. The distinction being drawn above is the one nobody else makes.

46 19paige_pharma, emma_london, tammy_FL and 43 others
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LabKate
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Apr 27, 2025 at 2:56 PM#13
PharmacoVig_BOS said:
Semaglutide structural biology relevant to the pharmacology: semaglutide is a 31-amino acid peptide with 94% homology to native GLP-1(7-36).

Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.

Ask again with the specifics and you will get a better answer than this one.

Last edited: Apr 27, 2025 at 5:56 PM
47 20Dr.SleepRoch, laura_annarbor, JenMemphis and 44 others
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DanielChem_CHI
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Apr 27, 2025 at 7:08 PM#14

One concrete data point for the thread. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

48 21ben_calgary, patPC_UT, Dr.DermMIA and 45 others
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Admin
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Apr 27, 2025 at 11:20 PM#15

Moderator note: a couple of off-topic posts removed.

49 22PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 46 others
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