Dr.RaviCardio said:My endo's protocol for lean mass plateau: if weight loss stalls for 6+ weeks at current dose, we go through this checklist before titrating up: Food…
OMG yes. lean mass + resistance training is the combo. Can confirm.
Dr.NutriCornell said:Right, and protein targets should be set on a reference weight rather than current weight.
This is exactly what I could not find anywhere else. Sending this to two other people who asked me the same thing last week.
Dr.RaviCardio said:My endo's protocol for lean mass plateau: if weight loss stalls for 6+ weeks at current dose, we go through this checklist before titrating up: Food…
Body composition tracking via bioimpedance on lean mass (InBody scan every 3 months):
| Metric | Baseline | Month 3 | Month 6 | Month 9 |
|---|---|---|---|---|
| Skeletal Muscle (lbs) | 75 | 73 | 67 | 71 |
| Body Fat (lbs) | 97 | 81 | 59 | 47 |
| Body Fat % | 39% | 33% | 28% | 21% |
| Visceral Fat (cm²) | 152 | 117 | 87 | 62 |
Note: skeletal muscle mass dipped initially then recovered with consistent resistance training + high protein. The visceral fat reduction is where the metabolic magic happens.
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Shop Reference Standardsdave_SLC said:I lifted three times a week throughout and still lost lean mass.
Muscle fiber type changes during GLP-1-mediated weight loss, relevant to lean mass: preliminary biopsy data suggests that weight loss shifts the skeletal muscle fiber type distribution:
This "metabolic remodeling" of muscle may contribute to improved insulin sensitivity independent of total lean mass changes. The muscle you keep becomes metabolically better, even if there's less of it[1].