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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab ResultsFrom 310 to 198 in 15 months — detailed timeline with labs

From 310 to 198 in 15 months — detailed timeline with labs

FitDadDave Tue, Jun 2, 2026 at 10:45 AM 24 replies 646 viewsPage 1 of 5
FitDadDave
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Jul 2024
Minneapolis, MN
Jun 2, 2026 at 10:45 AM#1

I got a full panel before starting and a repeat at three months, and the second one is more useful than the first purely because I now have something to compare against.

The bit I cannot resolve on my own is how often to repeat it, because quarterly seems to be the convention and I cannot find the reasoning.

I have searched first, so if this is covered somewhere point me at it and I will read it.

14 9Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 11 others
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Dr.SportsMedIN
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Feb 2024
Indianapolis, IN
Jun 2, 2026 at 10:51 AM#2

Short answer first, then the reasoning. Quarterly for the first year is convention rather than evidence, and it is defensible for a simple reason: it is roughly the interval over which HbA1c becomes informative again, since it reflects about three months of glycaemia. After the first year, and once doses are stable, annual is reasonable unless something specific is being followed.

13 8lisa_labSD, adam_van, Dr.SurgeonPGH and 10 others
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SandraNC_45
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Sep 2024
Charlotte, NC
Jun 2, 2026 at 10:57 AM#3
Dr.SportsMedIN said:
Quarterly for the first year is convention rather than evidence, and it is defensible for a simple reason: it is roughly the interval over which HbA1c…

That is correct as far as it goes, and here is where it stops going. One addition: if the lab changes analytical platform between your draws, the comparison breaks and nobody tells you. It is worth asking when a value moves inexplicably.

12 7NicoleRaleigh, james_edin, FranDenver and 9 others
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SallyK_inj
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567
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Jul 2024
Iowa
Jun 2, 2026 at 11:03 AM#4
FitDadDave said:
I got a full panel before starting and a repeat at three months, and the second one is more useful than the first purely because I now have something…

Same position here, arrived at the long way round. A defensible baseline is short: HbA1c and fasting glucose, a lipid panel with ApoB if you can get it, ALT and AST, creatinine with eGFR, TSH, ferritin and B12, and a full blood count. That set catches the things that change, the things that explain symptoms, and the things that alter the prescribing decision. Almost everything else on the long circulating lists is either invariant, uninterpretable without a specific question, or an incidental finding waiting to cause an unnecessary workup.

Last edited: Jun 2, 2026 at 12:03 PM
11 6tane_welly, Dr.PathRoch, mona_PHX and 8 others
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JenPlateau
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Nov 2024
Missouri
Jun 2, 2026 at 11:31 AM#5

Adding the clinical framing, because it changes how the question reads.

PSA: get baseline labs BEFORE starting baseline bloodwork therapy. You need a "before" picture to measure progress. My recommended pre-treatment panel:

  1. CMP + A1C + fasting insulin
  2. Complete lipid panel with particle count if possible
  3. hsCRP, ferritin, B12, vitamin D
  4. Thyroid panel (TSH + free T4)
  5. CBC with differential
  6. Liver panel (ALT, AST, GGT)
  7. DEXA scan or body composition

Total cost at Quest without insurance: ~$200. Worth every penny for the data.

10 5sarah_nash92, FitDadDave, RunnerRach and 7 others
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