lisa_labSD said:Receptor pharmacology relevant to the pharmacology: semaglutide is a GLP-1R agonist with a C-18 fatty acid chain that enables albumin binding (>99%),…
Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.
LindaRN_retired said:The pharmacokinetics explain nearly every practical question asked here.
Thank you for spelling out the reasoning rather than just the conclusion. Printing the relevant bit and taking it with me.
lisa_labSD said:Receptor pharmacology relevant to the pharmacology: semaglutide is a GLP-1R agonist with a C-18 fatty acid chain that enables albumin binding (>99%),…
Pushing back on lisa_labSD here. The objection nobody has made: this only works if the measurement is doing what we assume it is doing, and that assumption has not been tested here.
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Shop Reference StandardsOne concrete data point for the thread. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.
Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Tagging this one for the weekly digest.