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ForumsOther Peptides & Research CompoundsPeptide stability and storage — 12 month update Page 2

Peptide stability and storage — 12 month update

Dr.AddMedPHL Fri, Jan 31, 2025 at 1:51 PM 50 replies 2,433 viewsPage 2 of 10
RetaRick_CA
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Feb 2, 2025 at 12:48 AM#6
julia.endo said:
Storage question about storage and cold: my pen was left out of the fridge for 6 hours.

Storage best practices for compounded storage and cold:

  • Unreconstituted lyophilized powder: refrigerate (36-46°F), good for 12+ months
  • Reconstituted vials: refrigerate, use within 28 days
  • Pre-filled pens: refrigerate until first use, then room temp OK for 28 days
  • Never freeze reconstituted peptides — ice crystals damage the protein
  • Protect from light — store in original box or wrap in foil

When in doubt, refrigerate. Temperature abuse is the #1 cause of reduced potency in compounded peptides.

10 5SkepticalSean, Dr.CardioMD, EndoResFellow and 7 others
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labquiet_amy
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Feb 2, 2025 at 2:47 PM#7

One concrete data point for the thread. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

Last edited: Feb 2, 2025 at 4:47 PM
9 4HPLC_Greg, LibrarianMeg, bri_stats and 6 others
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VanRx_Mike
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Feb 3, 2025 at 4:46 AM#8
RetaRick_CA said:
Storage best practices for compounded storage and cold: Unreconstituted lyophilized powder: refrigerate (36-46°F), good for 12+ months Reconstituted…

Adding the part of the answer the thread has not reached. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.

8 3Admin, Dr.Martinez, mike_mod and 5 others
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stefan_berlin
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Feb 3, 2025 at 6:46 PM#9

A narrower follow-up, since the general answer is now clear:

Was that from a primary source or from a summary of one?

7 2TirzTom, TrialTracker_MD, JennaRN and 4 others
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Dr.AddMedPHL
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Philadelphia, PA
Feb 6, 2025 at 1:57 PM#10

OP back with an update, since a thread like this is useless without one.

Update: the excursion was survivable and the vial was fine. I now keep a cheap fridge thermometer, which costs nothing and ends the argument.

39 12JessicaM_2024, TomFromTexas, mike.trainer_LA and 36 others
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