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Evidence-based GLP-1 & peptide discussion since 2023
ForumsExercise & Body CompositionHow do you exercise when you barely have energy to exist — 12 month update

How do you exercise when you barely have energy to exist — 12 month update

Dr.EndoIndy Tue, Dec 2, 2025 at 2:19 PM 9 replies 1,051 viewsPage 1 of 2
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Dr.EndoIndy
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Oct 2024
Indianapolis, IN
Dec 2, 2025 at 2:19 PM#1

Training four times a week throughout and the scale has barely acknowledged it, which is demoralising in a way I did not expect.

What I actually want to know is what training is actually for during a large deficit, because framing it as calorie burn sets people up to quit when the arithmetic disappoints them.

Happy to be told the question itself is wrong.

5 0mia_MS2, LeilaHI, marcus_mpls and 2 others
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PharmacoVig_BOS
Senior Member
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8,901
Feb 2024
Boston, MA
Dec 2, 2025 at 3:07 PM#2
Dr.EndoIndy said:
Training four times a week throughout and the scale has barely acknowledged it, which is demoralising in a way I did not expect.

Exercise transformation with training: went from barely able to walk a block to completing a 10K last weekend.

My fitness journey alongside GLP-1 therapy:

  • Month 1-2: Walking 15 min/day
  • Month 3-4: Walking 30-45 min, started bodyweight exercises
  • Month 5-6: Joined a gym, started resistance training
  • Month 7+: Running, lifting heavy, swimming for fun

The weight loss made movement possible. The movement made more weight loss possible. Virtuous cycle in action.

4 24Dr.GutHealth, amsterdam_pete, LondonLisa and 1 other
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SallyK_inj
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Jul 2024
Iowa
Dec 2, 2025 at 3:55 PM#3
PharmacoVig_BOS said:
Exercise transformation with training: went from barely able to walk a block to completing a 10K last weekend.

Exercise-induced nausea amplification with training: I learned the hard way that intense exercise within 36 hours of injection can make nausea much worse. The combination of delayed gastric emptying + exercise-induced blood flow redistribution is rough on the GI system.

My workaround: inject Friday evening, do low-intensity activity Saturday, and save my intense workouts for Tuesday-Thursday when the GI effects have subsided. Timing your training around your injection schedule is a real optimization strategy.

3 23oliver_london, tane_welly, Dr.PathRoch
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bri_stats
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May 2024
Seattle, WA
Dec 2, 2025 at 4:43 PM#4
Dr.EndoIndy said:
Training four times a week throughout and the scale has barely acknowledged it, which is demoralising in a way I did not expect.

Second this. Posting only so the count is not one.

Last edited: Dec 2, 2025 at 8:43 PM
2 22JessicaM_2024, TomFromTexas
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TrialTracker_MD
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Jan 2024
Maryland
Dec 2, 2025 at 9:16 PM#5

Clinical perspective, offered as context rather than as advice.

Pet owner bonus of training: my dog is also losing weight because we're walking 2-3x more than before. His vet is thrilled. 🐕

We went from a 10-minute shuffle around the block to 45-minute walks through the neighborhood. He's more energetic, I'm more energetic, and we're both healthier.

Get a dog. Or borrow one. Walking a dog is the best low-impact exercise motivation that exists. They never let you skip a walk. 🐾

1 21lori_vegas
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