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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab ResultsMarathon PR after 80 lbs weight loss — race day report Page 3

Marathon PR after 80 lbs weight loss — race day report

MikeNYC_runner Mon, May 25, 2026 at 3:02 PM 25 replies 875 viewsPage 3 of 5
JessicaH_TX
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May 28, 2026 at 7:16 AM#11
Dr.RenalNash said:
The useful move here is to separate what is established from what is widely repeated.

True, and it depends on a baseline nobody has stated. Without knowing where someone started, the same number can be an excellent result or a disappointing one.

21 19wendy_avl, jason_paloalto, Dr.LeslieOBGYN and 18 others
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FranDenver
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May 28, 2026 at 11:05 AM#12
HealthEcon_DC said:
Weight is a noisy signal — daily variation of one to two kilograms from glycogen, sodium and gut contents — so a fortnight of flat readings is well…

This answered a question I did not know how to ask. Adding it to my notes with a link back to this thread.

22 20LipidDoc_ATL, BariatricNurseD, MASHdoc_SA and 19 others
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SteveThurs
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May 28, 2026 at 2:54 PM#13
Dr.RenalNash said:
The useful move here is to separate what is established from what is widely repeated.

I read this differently from Dr.RenalNash, on substance rather than tone. Not convinced. The evidence being cited is consistent with the conclusion and also consistent with two other conclusions nobody has ruled out.

23 21SleepFixSam, PurityPaulOR, MaxMetOK and 20 others
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NicoleRaleigh
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May 28, 2026 at 6:42 PM#14

The figures, for anyone assembling their own picture. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

Last edited: May 28, 2026 at 7:42 PM
24 22VendorMark, COA_Karl, MikeFit_NJ and 21 others
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Admin
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May 28, 2026 at 10:30 PM#15

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part.

25 23PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 22 others
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