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Evidence-based GLP-1 & peptide discussion since 2023
ForumsExercise & Body CompositionThrew up at the gym on injection day - lesson learned — what worked for you?

Threw up at the gym on injection day - lesson learned — what worked for you?

mike_mod Tue, Nov 18, 2025 at 3:26 PM 49 replies 1,391 viewsPage 1 of 10
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mike_mod
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Nov 18, 2025 at 3:26 PM#1

Training four times a week throughout and the scale has barely acknowledged it, which is demoralising in a way I did not expect.

What I am trying to establish is what training is actually for during a large deficit, because framing it as calorie burn sets people up to quit when the arithmetic disappoints them.

Tell me what I have not thought of.

5 0PharmHunterJen, TomTeleRx, DoseLogDan and 2 others
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julia.endo
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Nov 18, 2025 at 4:03 PM#2
mike_mod said:
Training four times a week throughout and the scale has barely acknowledged it, which is demoralising in a way I did not expect.

Exercise transformation with training: went from barely able to walk a block to completing a half marathon last Saturday.

My fitness journey alongside GLP-1 therapy:

  • Month 1-2: Walking 15 min/day
  • Month 3-4: Walking 30-45 min, started bodyweight exercises
  • Month 5-6: Joined a gym, started resistance training
  • Month 7+: Running, lifting heavy, cycling for fun

The weight loss made movement possible. The movement made more weight loss possible. Virtuous cycle in action.

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DerekSJ_a1c
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Nov 18, 2025 at 4:40 PM#3
julia.endo said:
Exercise transformation with training: went from barely able to walk a block to completing a half marathon last Saturday.

Pet owner bonus of training: my dog is also losing weight because we're walking 2-3x more than before. His vet is thrilled. 🐕

We went from a 15-minute shuffle around the block to 60-minute walks through the neighborhood. He's more energetic, I'm more energetic, and we're both healthier.

Get a dog. Or borrow one. Walking a dog is the best low-impact exercise motivation that exists. They never let you skip a walk. 🐾

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mel_PDX
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Nov 18, 2025 at 5:17 PM#4
mike_mod said:
Training four times a week throughout and the scale has barely acknowledged it, which is demoralising in a way I did not expect.

Mine went the same way, slower. Posting only so the count is not one.

2 22BiostatsBrad, PeptideSynthNJ
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Dr.Martinez
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Nov 18, 2025 at 8:44 PM#5

Adding the clinical framing, because it changes how the question reads.

Gym confidence after training weight loss: walked into a gym for the first time in 12 years yesterday. Was terrified. But you know what? Nobody stared. Nobody judged. Everyone was focused on their own workout.

Started with 20 minutes on the treadmill and some machine-based resistance exercises. Nothing fancy. But I DID IT. And I'll go back tomorrow.

To anyone too intimidated to start: the hardest rep is walking through the door. Everything after that is just movement. 💪

Last edited: Nov 19, 2025 at 1:44 AM
1 21adam_van
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