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Evidence-based GLP-1 & peptide discussion since 2023
ForumsExercise & Body CompositionZone 2 cardio + GLP-1: synergistic metabolic benefits — need advice

Zone 2 cardio + GLP-1: synergistic metabolic benefits — need advice

NauseaFreeNow Sun, Oct 12, 2025 at 1:59 PM 10 replies 1,173 viewsPage 1 of 2
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NauseaFreeNow
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Aug 2024
Indiana
Oct 12, 2025 at 1:59 PM#1

I trained through the whole thing, three times a week, and the effect on the scale was almost nothing while the effect on everything else was large.

What would genuinely help is knowing what training is actually for during a large deficit, because framing it as calorie burn sets people up to quit when the arithmetic disappoints them.

Happy to be told the question itself is wrong.

5 0stefan_berlin, Dr.EM_Chicago, pete_RVA and 2 others
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LarryQC_SD
Senior Member
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Jan 2024
San Diego, CA
Oct 12, 2025 at 2:13 PM#2
NauseaFreeNow said:
I trained through the whole thing, three times a week, and the effect on the scale was almost nothing while the effect on everything else was large.

Pet owner bonus of training: my dog is also losing weight because we're walking 2-3x more than before. His vet is thrilled. 🐕

We went from a 5-minute shuffle around the block to 30-minute walks through the neighborhood. He's more energetic, I'm more energetic, and we're both healthier.

Get a dog. Or borrow one. Walking a dog is the best low-impact exercise motivation that exists. They never let you skip a walk. 🐾

Last edited: Oct 12, 2025 at 3:13 PM
4 24paul_denver, TinaHashiRN, robert_kc and 1 other
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MikeKY_noInsulin
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Oct 2024
Louisville, KY
Oct 12, 2025 at 2:27 PM#3
LarryQC_SD said:
Pet owner bonus of training: my dog is also losing weight because we're walking 2-3x more than before.

Gym confidence after training weight loss: walked into a gym for the first time in 12 years yesterday. Was terrified. But you know what? Nobody stared. Nobody judged. Everyone was focused on their own workout.

Started with 20 minutes on the treadmill and some machine-based resistance exercises. Nothing fancy. But I DID IT. And I'll go back tomorrow.

To anyone too intimidated to start: the hardest rep is walking through the door. Everything after that is just movement. 💪

3 23Dr.SportsMedIN, amy_econ_NJ, bbq_ray_KC
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pete_RVA
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Richmond, VA
Oct 12, 2025 at 2:41 PM#4
NauseaFreeNow said:
I trained through the whole thing, three times a week, and the effect on the scale was almost nothing while the effect on everything else was large.

Second this. The detail I would add is minor and it is already implied above.

Last edited: Oct 12, 2025 at 7:41 PM
2 22MikeNYC_runner
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TrialTracker_MD
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Jan 2024
Maryland
Oct 12, 2025 at 3:54 PM#5

From the other side of the consultation, briefly.

Exercise transformation with training: went from barely able to walk a block to completing a 5K last month.

My fitness journey alongside GLP-1 therapy:

  • Month 1-2: Walking 15 min/day
  • Month 3-4: Walking 30-45 min, started bodyweight exercises
  • Month 5-6: Joined a gym, started resistance training
  • Month 7+: Running, lifting heavy, yoga for fun

The weight loss made movement possible. The movement made more weight loss possible. Virtuous cycle in action.

Last edited: Oct 12, 2025 at 8:54 PM
1 21lori_vegas
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