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ForumsMASH / Liver DiseaseHas anyone dealt with de novo lipogenesis reduction on glp-1? Page 7

Has anyone dealt with de novo lipogenesis reduction on glp-1?

NurseLeah_Nash Tue, Nov 18, 2025 at 1:33 AM 34 replies 1,698 viewsPage 7 of 7
Dr.GutHealth
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Nov 28, 2025 at 5:18 AM#31

Clinical perspective, offered as context rather than as advice. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

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lori_vegas
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Nov 28, 2025 at 1:46 PM#32
Dr.GutHealth said:
It helps to ask what evidence would change your mind before you look at any.

Same experience, arrived at from the opposite direction.

Last edited: Nov 28, 2025 at 3:46 PM
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PurityPaulOR
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Nov 28, 2025 at 10:14 PM#33
Dr.GutHealth said:
It helps to ask what evidence would change your mind before you look at any.

Adding the part of the answer the thread has not reached. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

Correct me if the detail matters more than I have assumed.

Last edited: Nov 29, 2025 at 1:14 AM
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BethLabQueen
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Nov 29, 2025 at 6:41 AM#34

The figures, for anyone assembling their own picture. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

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pete_RVA
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Nov 29, 2025 at 3:08 PM#35

A narrower follow-up, since the general answer is now clear:

What did you change at the same time, and can you separate the two now?

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