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ForumsOther Peptides & Research CompoundsBPC-157 systemic vs local effects — September 2026 Page 7

BPC-157 systemic vs local effects — September 2026

SleepFixSam Fri, Oct 18, 2024 at 7:05 PM 35 replies 2,053 viewsPage 7 of 7
maya_sedona
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Oct 28, 2024 at 2:42 AM#31

Following on from MASHdoc_SA — and this may be the naive question:

What did you change at the same time, and can you separate the two now?

Last edited: Oct 28, 2024 at 6:42 AM
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sarah.morrison
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Oct 28, 2024 at 4:05 PM#32
SleepFixSam said:
Update — tachyphylaxis to the gastric effect, persistence of the appetite effect.

I read this differently from SleepFixSam, on substance rather than tone. The objection nobody has made: this only works if the measurement is doing what we assume it is doing, and that assumption has not been tested here.

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quinn_sf
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Oct 29, 2024 at 5:28 AM#33
SleepFixSam said:
Update — tachyphylaxis to the gastric effect, persistence of the appetite effect.

Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.

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Dr.NutriCornell
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Oct 29, 2024 at 6:50 PM#34
SleepFixSam said:
Update — tachyphylaxis to the gastric effect, persistence of the appetite effect.

That reframing is the part I needed. Printing the relevant bit and taking it with me.

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Dr.DermMIA
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Oct 30, 2024 at 8:12 AM#35

Clinical perspective, offered as context rather than as advice. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.

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