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ForumsMASH / Liver DiseaseFibrosis regression on GLP-1 — looking for input Page 5

Fibrosis regression on GLP-1 — looking for input

oliver_london Mon, Nov 10, 2025 at 9:38 PM 23 replies 1,403 viewsPage 5 of 5
LipidDoc_ATL
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Nov 27, 2025 at 10:52 AM#21
Dr.SleepRoch said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

Adding the part of the answer the thread has not reached. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

Last edited: Nov 27, 2025 at 3:52 PM
50 23rachel_ABQ, traveltech_sara, AttorneyGrant and 47 others
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TirzTom
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Dec 2, 2025 at 2:47 PM#22

One concrete data point for the thread. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

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Dr.PulmRoch
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Dec 7, 2025 at 6:39 PM#23

Following on from Dr.SleepRoch — and this may be the naive question:

Did your prescriber agree with that reading, and if not what was their objection?

2 0AttorneyGrant, DebRD_ATL
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emily_PDX
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Dec 12, 2025 at 10:28 PM#24
TirzTom said:
If you are going to change something, change one thing and give it long enough to express itself.

Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.

3 1Dr.KarenChen, Dr.NateNeph, PharmD_Rodriguez
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ricardo_MIA
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Dec 18, 2025 at 2:14 AM#25
TirzTom said:
If you are going to change something, change one thing and give it long enough to express itself.

Right, and the exception is worth naming rather than left implied, because the exception is where people get into trouble.

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