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ForumsMASH / Liver DiseaseMASH biomarker panel — need advice Page 3

MASH biomarker panel — need advice

carl_compliance Mon, Nov 3, 2025 at 2:44 PM 14 replies 1,207 viewsPage 3 of 3
Dr.NephBHM_UK
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Nov 4, 2025 at 6:45 AM#11
DeniseRN_TPA said:
A defensible baseline is short: HbA1c and fasting glucose, a lipid panel with ApoB if you can get it, ALT and AST, creatinine with eGFR, TSH, ferritin…

Thank you — that is the clearest version of this I have read, and I have read a lot of them. Adding it to my notes with a link back to this thread.

3 1Dr.CardioMD, EndoResFellow, PharmacoVig_BOS
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Dr.CardioMD
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Nov 4, 2025 at 2:07 PM#12

Adding the clinical framing, because it changes how the question reads.

Shot day Wednesday report relevant to baseline bloodwork:

Week 25. Currently on 1.7mg. Down 41 lbs from starting weight of 253 lbs.

This week's observations: Mild fatigue day 1-2 post-injection, then fine.

Labs due next week — looking forward to seeing the metabolic panel. I'll post results in the Lab Results section when they come in.

Last edited: Nov 4, 2025 at 8:07 PM
4 2Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 1 other
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Dr.RaviCardio
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Nov 4, 2025 at 9:29 PM#13
TrialNerd_Beth said:
The liver data is among the strongest non-weight findings in the class.

Blood work came back perfect. baseline bloodwork + this community = winning. 🏆

Last edited: Nov 4, 2025 at 10:29 PM
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raj_cambridge
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Nov 5, 2025 at 4:51 AM#14
carl_compliance said:
The single most useful discipline is bringing the whole panel to a clinician rather than one flagged value.

PSA: get baseline labs BEFORE starting baseline bloodwork therapy. You need a "before" picture to measure progress. My recommended pre-treatment panel:

  1. CMP + A1C + fasting insulin
  2. Complete lipid panel with particle count if possible
  3. hsCRP, ferritin, B12, vitamin D
  4. Thyroid panel (TSH + free T4)
  5. CBC with differential
  6. Liver panel (ALT, AST, GGT)
  7. DEXA scan or body composition

Total cost at Quest without insurance: ~$200. Worth every penny for the data.

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mike_mod
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Nov 5, 2025 at 12:13 PM#15

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful.

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