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ForumsMASH / Liver DiseaseLiver enzymes normal for the first time in a decade — looking for input Page 5

Liver enzymes normal for the first time in a decade — looking for input

DataDave Wed, Sep 10, 2025 at 2:47 AM 32 replies 1,580 viewsPage 5 of 7
Dr.LeslieOBGYN
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Sep 28, 2025 at 10:55 AM#21

Following on from lisa_labSD — and this may be the naive question:

What did you change at the same time, and can you separate the two now?

34 7Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 31 others
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MASHdoc_SA
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Aug 2024
San Antonio, TX
Oct 5, 2025 at 1:12 AM#22
julia.endo said:
Worth answering the question that was asked rather than the one behind it.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.

35 8TrialTracker_MD, JennaRN, LabKate and 32 others
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tampaLisa73
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Oct 2024
Tampa, FL
Oct 11, 2025 at 3:25 PM#23
julia.endo said:
Worth answering the question that was asked rather than the one behind it.

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.

36 9sarah_nash92, FitDadDave, RunnerRach and 33 others
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roxy_nash
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Oct 18, 2025 at 5:34 AM#24
julia.endo said:
Worth answering the question that was asked rather than the one behind it.

That reframing is the part I needed.

37 10Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 34 others
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Dr.BariatricHTX
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Feb 2024
Houston, TX
Oct 24, 2025 at 7:39 PM#25

Adding the clinical framing, because it changes how the question reads. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

38 11maya_sedona, stefan_berlin, Dr.EM_Chicago and 35 others
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