Adding the clinical framing, because it changes how the question reads. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.
DeniseRN_TPA said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
I read this differently from DeniseRN_TPA, on substance rather than tone. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.
DeniseRN_TPA said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
Correct as far as it goes. The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.
Sigma-Aldrich — Research-Grade Standards
Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.
Shop Reference StandardsDeniseRN_TPA said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
Saving this. It is the first explanation that did not require me to already understand it.
Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Carry on.