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ForumsMASH / Liver DiseaseSurvodutide MASH Phase 2b — March 2026 Page 2

Survodutide MASH Phase 2b — March 2026

CanadaChris Fri, Aug 15, 2025 at 9:27 PM 31 replies 1,956 viewsPage 2 of 7
labquiet_amy
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Aug 15, 2025 at 11:45 PM#6
Dr.PainCLE said:
The liver data is among the strongest non-weight findings in the class.

Pushing back on Dr.PainCLE here. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

25 20TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 22 others
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Dr.NateNeph
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Aug 16, 2025 at 12:40 AM#7

The figures, for anyone assembling their own picture. With resmetirom now available for MASH, combination approaches are being explored, so the standard of care in this area is moving faster than most threads assume.

24 19NauseaFreeNow, SteveThurs, B12Beth and 21 others
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BariatricNurseD
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Aug 16, 2025 at 1:35 AM#8
labquiet_amy said:
Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this…

There is a second half to this that has not been said yet. It helps to say which part of this you are uncertain about. A precise question gets a precise answer; a general one gets everybody’s favourite anecdote.

Last edited: Aug 16, 2025 at 6:35 AM
23 18josh_phd_bmore, roxy_nash, tony_orlando and 20 others
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rachel_ABQ
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Aug 16, 2025 at 2:30 AM#9

One thing that is still open after NurseKim_ATL’s answer:

Whether normalised enzymes tell you anything about fibrosis, and what the right follow-up measurement is?

22 17SkepticalSean, Dr.CardioMD, EndoResFellow and 19 others
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CanadaChris
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Aug 16, 2025 at 6:52 AM#10

Reporting back.

Update — I was wrong in the opening post, specifically about the direction. Correcting it here rather than editing it away.

24 22lori_vegas, Dr.PulmRoch, maya_sedona and 21 others
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