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ForumsSide Effects & ManagementFAERS pharmacovigilance data for semaglutide — looking for input Page 2

FAERS pharmacovigilance data for semaglutide — looking for input

B12Beth Sun, Feb 8, 2026 at 6:51 AM 11 replies 898 viewsPage 2 of 3
chris_chi24
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389
1,678
Sep 2024
Chicago, IL
Feb 8, 2026 at 12:51 PM#6

For anyone in a physically demanding role:

  • Start your medication on a stretch of days off if possible, so you can gauge your response
  • Don't under-eat. Set a caloric floor (1500+ for active jobs) and hit it even when not hungry
  • Frontload your calories — bigger breakfast before a shift, not a big dinner after
  • Electrolyte packets (LMNT, Liquid IV, etc.) during shifts
  • If fatigue is severe enough to impact patient safety or job performance, that's a conversation with your prescriber about dosing schedule or slower titration

The fatigue is almost always worst in the first 4-6 weeks and improves as your body adapts to both the drug and the new caloric baseline.

40 10nick_newbie, DadBodDave, AmyNC_wife and 37 others
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mike_mealprep
Member
412
1,890
Jul 2024
Chicago, IL
Feb 8, 2026 at 3:13 PM#7

One thing that's helped me enormously: strategic caffeine timing. I have coffee at 7am and green tea at 1pm. Not more, not later. Gives me two energy bumps without wrecking my sleep. And I eat a high-protein snack (Greek yogurt, handful of almonds, string cheese) between meals to prevent energy crashes. Small things but they add up.

39 9newstart_MO, mia_MS2, LeilaHI and 36 others
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SaraMom3
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456
2,345
Aug 2024
Ohio
Feb 8, 2026 at 5:35 PM#8

Okay, reality check received. I tracked everything carefully yesterday and I ate... 1,050 calories. I'm basically intermittent starving, not intermittent fasting. Going to make a conscious effort to hit 1,400 minimum starting today and get bloodwork done this week. Thank you all.

Last edited: Feb 8, 2026 at 9:35 PM
38 8KetoKyle, CanadaChris, ZaraB_AL and 35 others
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