Adding the clinical framing, because it changes how the question reads. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
PharmHunterJen said:There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
Same pattern here, and in the same order. The detail I would add is minor and it is already implied above.
PharmHunterJen said:There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
Coming at PharmHunterJen’s question from a different direction. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.
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Shop Reference StandardsThe figures, for anyone assembling their own picture. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.
That is the short version; the long version is somebody else's post.
Closing the loop on my own question.
Coming back a few months on. It held. Nothing dramatic to report, which is the report.