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ForumsSemaglutide (Ozempic / Wegovy)Semaglutide and gut microbiome changes — looking for input Page 6

Semaglutide and gut microbiome changes — looking for input

NurseAsh_DET Wed, Sep 11, 2024 at 11:07 PM 41 replies 2,544 viewsPage 6 of 9
JakeSmashed95
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Dec 3, 2024 at 9:45 AM#26
Dr.PulmRoch said:
The version of this that has an answer is narrower than the version being asked.

There is a second half to this that has not been said yet. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

30 3Dr.PainCLE, mike_mealprep, NicoleRaleigh and 27 others
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SleepDoc_PDX
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Dec 14, 2024 at 10:30 AM#27

The figures, for anyone assembling their own picture. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

Last edited: Dec 14, 2024 at 1:30 PM
31 4hank_denver, carlos_SATX, sophie_paris and 28 others
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AussieAnna
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Dec 25, 2024 at 11:09 AM#28

Following on from Dr.PulmRoch — and this may be the naive question:

How much of the between-person variation is pharmacokinetic and how much is just adherence measured badly?

32 5LibrarianMeg, bri_stats, pete_manc_UK and 29 others
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DanielChem_CHI
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Jan 5, 2025 at 11:42 AM#29
SleepDoc_PDX said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.

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NurseAsh_DET
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Jan 16, 2025 at 12:08 PM#30

OP back with an update, since a thread like this is useless without one.

Six weeks on from posting: I stopped reading the weekly number and started reading a four-week average, and the "stall" I opened this thread about was a 1.8kg loss I could not see.

5 3emily_PDX, Dr.SleepRoch, laura_annarbor and 2 others
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