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ForumsSide Effects & ManagementDiarrhea vs constipation on GLP-1 — anyone have experience? Page 4

Diarrhea vs constipation on GLP-1 — anyone have experience?

HPLC_Greg Sun, Jan 4, 2026 at 3:28 AM 21 replies 1,190 viewsPage 4 of 5
MarkLI_maint
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Jan 21, 2026 at 12:53 AM#16
ingrid_STO said:
Gastric emptying studies and constipation: semaglutide delays gastric emptying by ~40% at steady state, as measured by acetaminophen absorption…

This matches mine closely enough to be worth saying so out loud. Nothing to add that would improve it.

Last edited: Jan 21, 2026 at 5:53 AM
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hyun_seoul
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Seoul, KR
Jan 23, 2026 at 2:48 PM#17
BethLabQueen said:
Gastroparesis symptoms with constipation: the delayed gastric emptying from GLP-1 agonists can cause early satiety, bloating, and feeling "full" for…

Genuinely useful, thank you. I had the facts and not the framework.

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LibrarianMeg
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Jan 26, 2026 at 4:42 AM#18

Adding the clinical framing, because it changes how the question reads. It helps to say which part of this you are uncertain about. A precise question gets a precise answer; a general one gets everybody’s favourite anecdote.

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Dr.NephBHM_UK
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Jan 28, 2026 at 6:34 PM#19
LibrarianMeg said:
It helps to say which part of this you are uncertain about.

Second this. The detail I would add is minor and it is already implied above.

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mike_mod
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Jan 31, 2026 at 8:25 AM#20

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source.

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