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ForumsMASH / Liver DiseaseMASH prevalence in GLP-1 users — November 2025 Page 7

MASH prevalence in GLP-1 users — November 2025

tampaLisa73 Wed, Jun 4, 2025 at 3:50 AM 44 replies 2,251 viewsPage 7 of 9
wei_SG
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Jun 11, 2025 at 3:35 PM#31
jim_asheville said:
Start from the measurement rather than the conclusion.

Adding the part of the answer the thread has not reached. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

11 9WendyG_ATL, SaraMom3, Dr.MetabolicMD and 8 others
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anders_CPH
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Jun 12, 2025 at 1:52 AM#32

Adding the numbers, since they settle part of this. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

12 10MariaRD, AussieAnna, BethLabQueen and 9 others
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DanielChem_CHI
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Jun 12, 2025 at 12:09 PM#33

A narrower follow-up, since the general answer is now clear:

How would you tell the difference between that and the alternative explanation?

13 11patPC_UT, Dr.DermMIA, fiona_VT and 10 others
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Dr.MetabolicMD
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Jun 12, 2025 at 10:26 PM#34
anders_CPH said:
If you are going to change something, change one thing and give it long enough to express itself.

Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.

Last edited: Jun 13, 2025 at 12:26 AM
14 12Dr.ObesityMed, HealthEcon_DC, PedsEndoPhilly and 11 others
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newstart_MO
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Jun 13, 2025 at 8:42 AM#35
anders_CPH said:
If you are going to change something, change one thing and give it long enough to express itself.

That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.

15 13RunnerRach, TrialNerd_Beth, HPLC_Greg and 12 others
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