🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsOther Peptides & Research CompoundsHas anyone dealt with kpv peptide for inflammatory bowel? Page 2

Has anyone dealt with kpv peptide for inflammatory bowel?

andrew_nyc Tue, Jan 23, 2024 at 8:45 PM 16 replies 2,158 viewsPage 2 of 4
Dr.SurgeonPGH
Senior Member
1,345
6,789
Mar 2024
Pittsburgh, PA
Jan 23, 2024 at 11:08 PM#6
DebRD_ATL said:
The escalation order that reflects the mechanism: water and salt first, then soluble fiber, then magnesium or an osmotic agent, then a stimulant only…

Worth saying plainly that not all of this is benign. Severe constipation on delayed gastric emptying has produced obstruction and ileus cases, rarely but genuinely. Pain with vomiting and no bowel movement is not a fiber conversation.

46 16DoseLogDan, SleepFixSam, PurityPaulOR and 43 others
Reply Quote Save Share Report
hank_denver
Member
278
1,234
Sep 2024
Denver, CO
Jan 24, 2024 at 12:03 AM#7
andrew_nyc said:
I added fiber, made it noticeably worse, and only later worked out that I had added the bulk without adding the water.

Gastroparesis symptoms with constipation: the delayed gastric emptying from GLP-1 agonists can cause early satiety, bloating, and feeling "full" for hours after a small meal.

Tips: eat your protein FIRST (most important macro), then vegetables, then carbs last. Chew thoroughly — 20-30 chews per bite isn't excessive. Avoid carbonated beverages with meals. If symptoms are severe, your doctor may recommend a gastric emptying study.

45 15raj_cambridge, ingrid_STO, pete_nash and 42 others
Reply Quote Save Share Report
Dr.RaviCardio
VIP Member
2,890
15,678
Jan 2024
New York, NY
Jan 24, 2024 at 12:58 AM#8
Dr.SurgeonPGH said:
Worth saying plainly that not all of this is benign.

Sulfur burps on constipation — the most underrated side effect nobody warned me about. 🤢 The smell is absolutely vile and comes on without warning.

What finally helped: eliminating eggs and cruciferous vegetables. Also, eating smaller portions and chewing thoroughly reduces the gas production.

If sulfur burps persist beyond 2-3 weeks, talk to your provider — it could indicate gastroparesis that needs medical attention.

44 14mark_tokyo, hans_munich, jason_sac26 and 41 others
Reply Quote Save Share Report

Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
mel_PDX
Member
189
890
Dec 2024
Portland, OR
Jan 24, 2024 at 1:53 AM#9

Following on from CanadaChris — and this may be the naive question:

Whether fiber actually helps GLP-1 constipation or whether the evidence is borrowed from a different population?

Last edited: Jan 24, 2024 at 7:53 AM
43 13BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 40 others
Reply Quote Save Share Report
andrew_nyc
Member
534
2,345
Apr 2024
New York, NY
Jan 24, 2024 at 6:16 AM#10

Reporting back.

Update — the osmotic agent was the thing. I had been reaching for a stimulant, which was making the next day worse.

23 21JessicaM_2024, TomFromTexas, mike.trainer_LA and 20 others
Reply Quote Save Share Report

Similar Threads

BPC-157 oral vs injectable — bioavailability review and evidence15 replies
TB-500 for tissue repair — mechanism and clinical evidence4 replies
Selank and Semax — anxiolytic peptides overview2 replies
CJC-1295/Ipamorelin combination — GH secretagogue discussion23 replies
BPC-157 + GLP-1 stacking for gut healing — N=1 experience17 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register