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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMASH / Liver DiseaseMy liver enzyme journey — need advice Page 3

My liver enzyme journey — need advice

james_edin Sun, Apr 6, 2025 at 9:12 AM 17 replies 1,791 viewsPage 3 of 4
TinaHashiRN
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Sep 2024
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Apr 12, 2025 at 7:14 AM#11
Dr.RaviCardio said:
Liver ultrasound comparison for liver and MASH: my hepatologist ordered serial ultrasounds to track NAFLD regression.

This is exactly what I could not find anywhere else. Adding it to my notes with a link back to this thread.

46 19SarahChen_PharmD, sarah.morrison, NeuroNate and 43 others
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jim_asheville
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Aug 2024
Asheville, NC
Apr 12, 2025 at 5:06 PM#12

Clinical perspective, offered as context rather than as advice. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.

47 20BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 44 others
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Dr.AddMedPHL
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Philadelphia, PA
Apr 13, 2025 at 2:57 AM#13
VanRx_Mike said:
ATTAIN trial (survodutide) context for liver and MASH: survodutide, a GLP-1/glucagon dual agonist, showed -18.7% body weight at 46 weeks in the Phase…

Pushing back on VanRx_Mike here. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.

48 21mike.trainer_LA, sarah_nash92, FitDadDave and 45 others
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Dr.NateNeph
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Apr 13, 2025 at 12:48 PM#14

Adding the numbers, since they settle part of this. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

49 22B12Beth, RickReta_CO, PharmHunterJen and 46 others
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mike_mod
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Apr 13, 2025 at 10:39 PM#15

Moderator note: a couple of off-topic posts removed.

Last edited: Apr 14, 2025 at 12:39 AM
50 23PurityPaulOR, MaxMetOK, MounjBrad and 47 others
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