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ForumsMASH / Liver DiseaseAlcohol + MASH + GLP-1 — 6 month update Page 3

Alcohol + MASH + GLP-1 — 6 month update

matt_MKE Wed, Mar 26, 2025 at 11:39 PM 13 replies 1,673 viewsPage 3 of 3
RetaRick_CA
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Mar 31, 2025 at 4:50 AM#11
CarlaRPh_TPA said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.

41 14SkepticalSean, Dr.CardioMD, EndoResFellow and 38 others
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fiona_glasgow
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Apr 2, 2025 at 9:53 PM#12
JennaRN said:
Agreed, and ALT falling is not the same as fibrosis improving.

That reframing is the part I needed.

42 15TirzTom, TrialTracker_MD, JennaRN and 39 others
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tyler_CSCS
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Apr 5, 2025 at 2:55 PM#13
CarlaRPh_TPA said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.

Worth separating that from liver and MASH, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

43 16Dr.SportsMedIN, amy_econ_NJ, bbq_ray_KC and 40 others
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SleepDoc_PDX
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Apr 8, 2025 at 7:56 AM#14

Adding the numbers, since they settle part of this. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

Worth separating that from liver and MASH, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

44 17sophie_paris, mel_PDX, Dr.AddMedPHL and 41 others
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mike_mod
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Apr 11, 2025 at 12:55 AM#15

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Carry on.

45 18PurityPaulOR, MaxMetOK, MounjBrad and 42 others
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