One thing that is still open after sophie_paris’s answer:
Did your prescriber agree with that reading, and if not what was their objection?
Dr.AddMedPHL said:Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…
I read this differently from Dr.AddMedPHL, on substance rather than tone. Not convinced. The evidence being cited is consistent with the conclusion and also consistent with two other conclusions nobody has ruled out.
Dr.AddMedPHL said:Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…
That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.
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Shop Reference StandardsDr.AddMedPHL said:Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…
This answered a question I did not know how to ask. Printing the relevant bit and taking it with me.
Adding the clinical framing, because it changes how the question reads. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.