🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsSemaglutide (Ozempic / Wegovy)Heart rate increase on sema — what worked for you? Page 7

Heart rate increase on sema — what worked for you?

GraceAZ_72 Fri, Apr 5, 2024 at 2:21 AM 66 replies 3,533 viewsPage 7 of 14
JessicaH_TX
Senior Member
4,123
13,456
Dec 2023
Houston, TX
Apr 16, 2024 at 1:07 AM#31
GraceAZ_72 said:
Following this thread I went back and re-read the extension data properly.

Second this. Nothing to add that would improve it.

10 8wendy_avl, jason_paloalto, Dr.LeslieOBGYN and 7 others
Reply Quote Save Share Report
PurityPaulOR
Senior Member
1,890
7,890
Mar 2024
Oregon
Apr 16, 2024 at 8:54 PM#32
GraceAZ_72 said:
Following this thread I went back and re-read the extension data properly.

There is a second half to this that has not been said yet. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

11 9MikeNYC_runner and 8 others
Reply Quote Save Share Report
Dr.NateNeph
VIP Member
2,987
16,234
Dec 2023
Houston, TX
Apr 17, 2024 at 4:42 PM#33

Adding the numbers, since they settle part of this. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

12 10SteveThurs, B12Beth, RickReta_CO and 9 others
Reply Quote Save Share Report

Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
VendorMark
Senior Member
3,456
14,567
Jan 2024
Texas
Online
Apr 18, 2024 at 12:30 PM#34

A narrower follow-up, since the general answer is now clear:

How much of the between-person variation is pharmacokinetic and how much is just adherence measured badly?

13 11Dr.PeteFamMed, claudia_zurich, nancy_portland and 10 others
Reply Quote Save Share Report
maya_sedona
Member
289
1,234
Sep 2024
Sedona, AZ
Apr 19, 2024 at 8:18 AM#35
Dr.NateNeph said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

This is where I part company with the consensus forming above. The objection nobody has made: this only works if the measurement is doing what we assume it is doing, and that assumption has not been tested here.

14 12Dr.RaviCardio, jennifer_SEA, tyler_CSCS and 11 others
Reply Quote Save Share Report
15678914

Similar Threads

STEP 1-5 trials comprehensive summary — efficacy endpoints compiled12 replies
Oral semaglutide 50mg Phase 3 — OASIS program results16 replies
Semaglutide pharmacokinetics — half-life, Tmax, steady state modeling10 replies
Compounded semaglutide stability data — temperature and light sensitivity16 replies
0.25mg → 2.4mg titration: optimal schedule based on clinical data6 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register