Dr.PeteFamMed said:

On a suppressed appetite the winning strategy is protein density per unit of volume, not per calorie.

I will push back on the powder-first advice. It works and it also trains people out of eating food, and when the drug stops the habits are what remain. Getting protein from meals is slower and holds up better afterwards.

One concrete data point for the thread. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

DebRD_ATL said:

I will push back on the powder-first advice.

Coming at DebRD_ATL’s question from a different direction. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

Following on from Dr.CardioMD — and this may be the naive question:

Whether the RDA is the wrong reference entirely during rapid weight loss, and what the actual target should be?

Reporting back.

Front-loading was the answer. Same total intake, same drug, but two thirds of the protein before midday and I am hitting the target most days now.