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ForumsSide Effects & ManagementDay 3 on sema and I feel like death warmed over — need advice Page 10

Day 3 on sema and I feel like death warmed over — need advice

roxy_nash Sat, Aug 16, 2025 at 7:33 AM 50 replies 2,150 viewsPage 10 of 10
rick_sfbay
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Aug 30, 2025 at 4:32 PM#46

A narrower follow-up, since the general answer is now clear:

How long did you give it before you decided it was working?

8 6mike_mealprep, NicoleRaleigh, james_edin and 5 others
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roxy_nash
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Nashville, TN
Aug 31, 2025 at 4:15 AM#47

OP back with an update, since a thread like this is useless without one.

Holding the step for six weeks instead of four did it. Same dose, same food, and the nausea that had felt like a wall turned out to be a timing problem.

9 7roxy_nash, tony_orlando, Dr.NephBHM_UK and 6 others
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DebRD_ATL
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Aug 31, 2025 at 3:58 PM#48
jason_paloalto said:
Say what you would expect to see if you were wrong, before you look.

Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.

Last edited: Aug 31, 2025 at 7:58 PM
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DanielChem_CHI
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Sep 1, 2025 at 3:40 AM#49
jason_paloalto said:
Say what you would expect to see if you were wrong, before you look.

That reframing is the part I needed. Printing the relevant bit and taking it with me.

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paige_pharma
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Omaha, NE
Sep 1, 2025 at 3:22 PM#50

Clinical perspective, offered as context rather than as advice. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

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